xardoz

PIT & Clubhouse
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About xardoz

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    Rapid City, SD
  1. The NFL is ruining football for me. Referees should not decide games. That is the job of players and coaches. Too many subjective penalties.
  2. Just for thought..... https://www.vox.com/science-and-health/2018/8/29/17790118/alcohol-lancet-health-study “The safest level of drinking is none.” This was the stunning conclusion of a big paper that appeared last week in the Lancet — one that prompted dozens of news stories warning of the dangers of even the lowest levels of alcohol consumption. The researchers wanted to estimate alcohol use and the burden of alcohol-related disease in 195 countries. So they looked at more than 700 studies from around the world, involving millions of people, and came up with a statement about what safe drinking looks like. Their reasons for going to all this trouble were clear: Alcohol is a massive health and social problem worldwide. Excessive drinking can, over time, increase the risk of everything from liver disease to high blood pressure, injury, and memory and mental health problems. So getting a sense of the global health impact of drinking — the seventh leading risk factor for premature death and disease overall, they determined — was a worthwhile effort. “But while the paper is so nice and so useful [at estimating alcohol’s disease burden],” Stanford meta-researcher John Ioannidis told me, “at the last moment it destroys everything.” Instead of focusing on the message about the dangers of excessive drinking, “it focuses on making a claim that no alcohol use is safe.” Not only did the data in the paper not support a zero drinks recommendation, but the authors were also guilty of doing what too many nutrition researchers do: They used definitive, causal language to talk about studies that are only correlational. That’s something Ioannidis, a longtime critic of nutrition science, recently called out as a major source of confusion for the public. In a new paper, he argues that the field of nutritional epidemiology is in need of radical reform. The alcohol study, and the discussion around it, encapsulates everything that’s wrong with nutritional epidemiology and the way we talk about it. To avoid getting duped in the future, here’s what you need to know. The way we talk about nutrition science is wrong Most of what we know about nutrition’s effects on chronic disease comes from observational studies. With them, researchers track what large numbers of people eat over time and then look at their rates of disease, trying to tease out relationships in the data and generate hypotheses for future research. Do people who drink more red wine have lower rates of heart disease? Is eating yogurt and nuts linked with a longer life span? These studies aren’t controlled like randomized trials, where study participants are randomly split into groups and assigned to different interventions. That means the authors of observational studies can’t actually tell us whether one thing caused another thing to happen — only that two things are associated. Observational studies are also riddled with confounding factors, the unmeasured variables that may actually give rise to certain outcomes. For example: Say you want to compare people who drink spirits and beer to wine drinkers. These two groups of people might have other differences at the outset aside from their choices of boozy beverage. As we saw with another recent alcohol study, beer and spirit drinkers were more likely to be lower-income, male, and smokers and to have jobs that involved manual labor, compared with the wine drinkers. They had a higher risk of death and cardiovascular disease compared to wine drinkers, but was it those lifestyle factors — or just their choice of beer and spirits — that caused their disease risk to shoot up? Researchers try to control for these confounders but they can’t capture all of them. And even in the best-controlled studies of eating and drinking, it’s just incredibly difficult to tease out whether a single nutrient, food, or drink truly caused a specific health outcome. As Ioannidis points out in his new paper, “Individuals consume thousands of chemicals in millions of possible daily combinations.” We also prepare our foods in thousands of different ways, and when you add one thing to your diet, you take another away. Teasing out the influence of these variables on health outcomes is “challenging, if not impossible,” Ioannidis added. That’s why observational studies in nutrition are only supposed to be hypothesis-generating, not a source for definitive statements about how a single food or nutrient increased or decreased the risk of a disease by a specific percentage. You wouldn’t know that if you read the conclusions of nutrition studies and especially much of the reporting on nutrition studies. If someone meta-analyzed the evidence from cohort studies (a type of observational research) on various foods, Ioannidis writes, tongue in cheek: ... eating 12 hazelnuts daily (1 oz) would prolong life by 12 years (ie, 1 year per hazelnut), drinking 3 cups of coffee daily would achieve a similar gain of 12 extra years, and eating a single mandarin orange daily (80 g) would add 5 years of life. Conversely, consuming 1 egg daily would reduce life expectancy by 6 years, and eating 2 slices of bacon (30 g) daily would shorten life by a decade, an effect worse than smoking. All of these claims can’t possibly be true, and yet we often use this type of causal language to talk about nutrition results. “Readers and guideline developers may ignore hasty statements of causal inference and advocacy to public policy made by past nutritional epidemiology articles,” Ioannidis suggested in his new paper. And we — journalists, researchers, policymakers — should avoid making these types of statements based on nutritional epidemiology altogether. What the new alcohol paper really showed But unlike the spurious conclusions Ioannidis cited — about how eating a little bacon or an egg will shave years off your life — heavy levels of alcohol consumption have been proven to have terrible health consequences. “If eggs are bad, even if you eat eight eggs a day, this is no big deal, while with eight drinks of alcohol a day, the risk of disease and death is tremendous,” Ioannidis summed up. And since heavy drinking isn’t socially acceptable, there’s a high degree of underreporting that happens and a real chance that alcohol’s actual burden is underestimated. While no one disputes the damaging effects of heavy drinking, there is a lively debate about what constitutes healthy moderate drinking (and concern about the alcohol industry biasing research about the benefits of light drinking). But the new Lancet paper went much further and made the bold claim that people should drink nothing because even a single drink per day is problematic. To understand why this assertion is absurd, take a look at this figure from the study, which tracks how the risk of alcohol-related health problems increases by the number of drinks consumed each day: The relative risk of alcohol for all attributable causes, by standard drinks consumed per day. Lancet The authors focused on the risk increase between zero and one drinks per day, and suggested “consuming zero standard drinks daily minimized the overall risk of all health loss.” Yet you’ll notice the risk between zero and one, in the bottom left corner of the chart, is virtually indistinguishable. In fact, the risk curve only starts to increase after one drink, or even one and a half. So that’s why suggesting people don’t drink anything based on this data is misleading, Cecile Janssens, a research professor of epidemiology at Emory University, told Vox. “This paper shows that very heavy drinking is unhealthy,” she said, “but it doesn’t show that zero drinks is the safest.” The major result in the paper’s press release, and the one most highlighted in the news coverage, was that adults who consumed a single alcoholic beverage per day increased their risk of 23 alcohol-related health problems (from cancers to cardiovascular disease and personal injuries) by 0.5 percent compared to non-drinkers. Over at the New York Times, Aaron Carroll did a great job of putting this risk into perspective. A 0.5 percent relative risk increase between no drinking and one drink a day means four more people in 100,000 per year will experience an alcohol-related problem. Here’s Carroll: For each set of 100,000 people who have one drink a day per year, 918 can expect to experience one of the 23 alcohol-related problems in any year. Of those who drink nothing, 914 can expect to experience a problem. ... At two drinks per day, the number experiencing a problem increased to 977. Even at five drinks per day, which most agree is too much, the vast majority of people are unaffected. Put another way, statistician David Spiegelhalter estimated that 25,000 people would need to drink 400,000 bottles of gin to experience one extra health problem compared to non-drinkers, “which indicates a rather low level of harm in these occasional drinkers.” So again, the difference in health risk between those who drink nothing and those who have one daily drink is tiny — and, given the weak observational research it’s based on, potentially not meaningful. “Telling people not to drink anything is a stretch,” Ioannidis said. “We really need to have large randomized trial evidence to be able to make such a recommendation, and we don’t have one.” So for now, we don’t know the precise threshold over which alcohol consumption gets risky, but based on this study, it certainly looks like more than zero drinks. So perhaps the question is why the study authors, and the Lancet press office, stretched their findings so far. If I’m being generous, I’d say they were driven by a desire to draw attention to alcohol’s great health burden. But I think they were also playing into the public’s desire for wild nutrition claims — a desire we need to stop feeding.
  3. I am on board with Tuma, I hope I am wrong, but.... a. Too steep a price. b. Guy has talent but injury issues c. Not too much more than what we already have (Hill/Savage/JT).
  4. I have no issue with someone killing themselves. It sucks to watch, but that is their choice. Yet, most of us do some sort of "dangerous" activity every day. (Use too much salt, eat too many fats, failure to stop at a stop sign or signal a lane change) I have read articles in the past saying that trans-fats are the killer, later we find out they are not all that bad. Cholesterol raises it's head as the most dangerous health risk (notice the 'normal cholesterol' rate keeps dropping but heart disease has remained fairly steady.) From Heart.og ...Cardiovascular disease is the leading global cause of death, accounting for 17.3 million deaths per year, a number that is expected to grow to more than 23.6 million by 2030. Heart disease is the No. 1 killer of women, taking more lives than all forms of cancer combined. So alcohol is far down the list (I assume some of the numbers from the study made it into Cardiovascular disease and visa-versa as well) Studies are just that. A study. It is evidence. I think the conclusion of "no safe level" is a bit inflated. Yeah, alcohol is (generally) not good for you. Yeah, too much alcohol can kill you. So can too much cayenne pepper or sriracha sauce - but I like it and I use it. You cannot live life in a bubble, because there is a boogey-man around every corner. (I think I am going to have some fried pork-cutlets for lunch.... mmmmmm) Too much of anything is bad. How much and how bad, depends on the individual - their actions and reactions. I have no issue with the facts of the article, I have an issue with the inflamed hypothesis. When someone says, "no safe level" there is a bias to it. I bet we all know someone who drank and lived to be 90. I am related to one that had at least beer everyday and lived to be 105. I do not want to be 105, so maybe I should drink 2 beers a day. The article takes meta-analysis and tries to affect behavior with it. The article shows NO CORRELATION between this high-level data and the dangers on a personal level. It really does not break the data down. It casts a wide net to try and prove something that is more granular. It appears to be an attempt to use some statistics from many different and unrelated studies (and what was there scientific method?) In my wee-brain, it appears to be a classic case of inductive reasoning, and at best, is not good science, or does present good science. I always wonder who pays for these studies - usually you find that people make a study to prove something (i.e. positive alcolhol study may have been paid for by a company that sells booze or even cigarettes) Considering your background, I am kinda surprised to see you posting an article promoting prohibition. You know as well as I do, that prohibitions do not work in a free society - and only kinda work in closed or controlled societies. A related article also states: Experts say that if you're not a drinker, there aren't any health-related reasons for you to start. If you do drink, it's best to stay within the guidelines for moderate drinking, though there's no 100 percent safe level. For women, moderate means one drink a day; for men, two drinks. One drink is equal to 5 ounces of wine or a 12-ounce beer or one shot (1.5 ounce) of an 80-proof liquor. There was another article in that group that said moderate consumption lowers heart failure. Moderate alcohol consumption tied to lower heart failure risk So even from MedicalPress.com there are conflicting studies/articles. Which to believe? Next, someone is going to say there is "no safe level" of being an RogerGoodell - but here I am - killing it!
  5. The Black Label ads reminds me of the most disgusting beer I ever tasted. btw.... I was always a Ford guy. Give me a Galaxie XL with a 427 side oiler (7 litre) and a 4 speed toploader. Then again, there was the Fairlane Thunderbolt. https://www.hotrod.com/articles/hrdp-0911-ford-thunderbolt-reunion/
  6. To quote Garth Brooks: Sometimes I thank God for unanswered prayers
  7. One word: Moderation. Anything in excess is dangerous. Yes, I do know of families and relationships that have failed in part to the beloved "marijuana". There are positives and negatives to everything in the world. I will say, that it is not near the number that alcohol has, affected, but they do exist.
  8. 12-4 (SB win) Breezey will lead the league in passing (4800) and we will have 2 receivers over 1000 yards. Mark Ingram will break the all-time rushing yards record. Defense will be rated in the top 10.
  9. Then this article from Allsaintsconsidered.com Jeez, I do not know who to believe - these "expert" reporters or Sean https://www.allsaintsconsidered.com/single-post/2018/08/18/Setting-the-Scene-Rick-Leonard At long last, Setting the Scene continues with a look at Saints fourth-round surprise pick, Florida State RT Rick Leonard. Leonard is a converted defensive end, he changed positions when he went into the coach’s office to ask how he can help the team. After switching to offensive tackle throughout a single offseason, he won the starting job at FSU, but lost it after the first three games of the season. He then went on to start the final three games and the entire 2017 season at RT. Giving him a small sample size of 19 games. Which means that scouts didn’t have a ton of tape to look at, but he’s got a lot of tread left on the tires. His experience as a defensive end is valuable as he has a ton of athleticism and knows what to look for and counter from opposing ends. As always, I'll highlight each of the Saints incoming draft selections, discuss some pro comparisons and give a best-case scenario, worst-case scenario, and my expected stat lines for their first years. Just like last year, I’ll rule out the injury bug and give each prediction as if they were healthy from game 1 to game 16. I will, however, use the practice squad or possible preseason cut as options. Be forewarned, I didn't spend as much time with the combine on Tre'Quan's because there were other parallels I was more interested in.... (continued)
  10. Well, you kind of re-affirmed my point in the first paragraph. It seems you care about the content. Who cares what someone is saying? If it is slander or defamation, he can be sued - that is his business. Yet, if he did not have a following, people would not listen. However, because he says some distasteful things, you are validating a partial gag. The reality is, who cares about hurting someone's feelings. This is a little bigger than that. It sets a dangerous precedent. I do believe that this is a discrimination case - yet not one based on classifications as the courts outlined (suspect and semi-suspect classifications). I also hear what you say about the corporate policies. However, comparing employees to a customer using a service is different kind of contract (as stated by the SCOTUS). Also, Free Speech has (historically) been painted with a wide brush. Btw... I was not doing a 'final analysis'. I was asking a question, and making clarifying statements. I am really on the fence on this, but it is not passing the 'sniff test'. (If it smells like a skunk, it may be a skunk) This is also far from 'cut and dry', as I probably would not have even created this topic if I thought so. Just trying to have some dialectic. I know you listen to the media much more than I do - as do most people. However, I quit being programmed in 2007. I see InfoWars as the same thing as CNN, NBC, FOX etc... they all suck. (Infowars may be a little more entertaining)
  11. The issue I have with it is that this happened across several companies at the same time, which implies collusion. So, y'all agree that the Constitution only protects people from the government, not private enterprise. ..... I guess Bakers do not have to make cakes for gay couples or people of 'color'.
  12. Let's stir the pot a little. Last week, Apple, Facebook, Youtube and Spotify all have removed InfoWars and related content. What do y'all think of that? Is this not a violation of Free Speech? I know that this is not the government, but it is definitely not an individual or an individual companies effort.
  13. Soon the new Colour Rush uniforms will consist of pumps and knee-high skirts.
  14. These games are going to get long and tedious. ..... Gonna need to get a sleeping bag and camp out to see the end of the 4th quarter.